Drug Uses

Antivert is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body. Antivert is used to treat nausea, vomiting, and dizziness associated with motion sickness. Antivert may also be helpful in treating vertigo. This medicine may also be used for other purposes.

How Taken

Antivert comes as a regular and chewable tablet and a capsule. For motion sickness, Antivert should be taken 1 hour before you start to travel. Doses may be taken every 24 hours if needed. For dizziness caused by an ear condition, follow your doctor's directions. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Antivert exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. The chewable tablets may be chewed or swallowed whole.

Warnings/Precautions

This medicine may cause drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. This medicine will add to the effect of other depressants or alcohol. Ask your pharmacist if you have questions about which medicines are depressants. It is unknown if this medicine is excreted in breast milk. If you are or will be breast-feeding while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

Missed Dose

Since Antivert is usually taken as needed, missing a dose is usually not a problem. If you are taking Antivert on a regular schedule and you miss a dose, take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

Possible Side Effects

Stop taking Antivert and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives). Other, less serious side effects may be more likely to occur. Continue to take Antivert and talk to your doctor if you experience drowsiness or dizziness; a dry mouth (may be relieved by sugarless gum, ice chips, saliva substitutes, or other products if bothersome); blurred vision; nervousness; insomnia; or constipation. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Dispense in tight, light-resistant containers. Store at controlled room temperature 15°-30°C (59°-86° F).

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include unusual excitability, drowsiness, hallucinations, very slow or shallow breathing, and seizures.

More Information

Antivert may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all prescription and over-the-counter medicines that you are taking, and do not take any medicine without first talking to your doctor. Antivert is contraindicated in individuals who have shown a previous hypersensitivity to it. For more information, talk to your doctor, pharmacist or health care provider.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Science Daily — When he began his research on motion sickness, Tom Stoffregen thought finding test subjects would be difficult. After all, it's called motion sickness because it results in headaches, dizziness, and, often, literally being sick. What kind of people would be eager to find out what it takes to make them throw up?
Tom Stoffregen monitors an experiment on his computer as the writer plays test subject. (Photo by Patrick O'Leary)
U students, it turns out. A lot of them.
"Undergraduate students, as a class, are suicidal," Stoffregen says bluntly. "I'm flooded with volunteers." He suspects the mass offering of students may have something to do with misplaced pride. "People think, 'You can't make me throw up,'" he says. Unfortunately for them, Stoffregen, a professor in the College of Education and Human Development's School of Kinesiology, has invested a lot of time and effort into finding out exactly what brings on motion sickness. And, like an academic 007, he's got a license to test.
Stoffregen's interest in motion sickness goes back to his childhood, when he was interested in space flight. He knew some astronauts suffered motion sickness, and after studying motion in graduate school and working for NASA, he wanted to find out why.
People have been motion sick for thousands of years, says Stoffregen, conjuring visions of dizzy Neanderthals and green-faced Vikings, but no one is sure why.
"There's an intuitive assumption that motion sickness is caused by the inner ear," he says. So far, the only approach to the problem has been studying how the sensations in the inner ear and eyes are different in situations when motion sickness results. For example, when a person is in a car and the eyes report movement but the body thinks it's stationary. Stoffregen thinks, however, that these perceptual differences are not what causes motion sickness. After all, nearly every person on this planet has experienced those perceptual differences at some point or another, and if we all reacted by being motion sick, well, let's just say the world would be a much different place. We'd have to take pilgrimages instead of planes, for one thing, and the rides at Disneyland would become the stuff of children's nightmares.
But if perceptual differences are not the cause of motion sickness, then what is? Movement, says Stoffregen. He measures the movement of people subjected to his sickness-inducing tests, and "the people who are going to get sick commence to move in really weird ways," he says, imitating the type of staggering walk typical after tequila night at the bar. Even when the subjects are strapped to an upright stretcher, the ones who feel sick still move a little. "They wriggle," says Stoffregen. Due to individual differences to sensitivity, only about half of Stoffregen's test subjects feel sick. Those who don't also don't wriggle, which makes Stoffregen think that movement is the key factor behind motion sickness.
Stoffregen has tested his theory extensively in the University's Human Factors Research Laboratory. His tests are all designed to make a person feel motion sick, but the test subjects remain stationary while the scenery around them shifts. In one test, a room-like structure is set on metal tracks. The subject stands on a platform as the "room," which has three walls and a ceiling, slides forward and backward on the tracks. The effect of the moving room has also been computerized, so a subject can stand in front of a huge screen and feel the same effects. Stoffregen also has an Xbox in his lab, which he asks test subjects to play. He doesn't even need special games. "The games are so realistic now, they can make people sick," he explains.
Being an undergraduate myself (though not suicidal) it only seemed right to undergo one test. Stoffregen directed me to the moving room, where he placed a two-by-four board on the platform before standing me on it. An inch of my flip-flops extended past each edge of the two-by-four, placing me just slightly off-balance. The décor was hurl-worthy on its own: The walls and ceiling were covered in white wallpaper veined with blue, giving the room the air of a huge marble crypt, and the focal piece was a bland map of the United States that only added to the atmosphere.
Stoffregen told me to focus on the map, then pulled the room backward a few feet. The map came zooming at my face, and it felt as if the floor had tilted backward 45 degrees. I took an involuntary step back (off the two-by-four), certain that I would fall over otherwise. Test subjects often endure 30 to 40 minutes of this, Stoffregen said, but 30 seconds was enough for me. No macho pride here; I fully believed he could make me toss my cookies.
Interestingly enough, Stoffregen says that no one knows why motion sickness often results in nausea and vomiting. As yet there is no scientific explanatinon for why seasickness makes you spew, carsickness makes you blow chunks, roller coasters make you ralph, or transoceanic flights to Osaka will make your stomach say sayonara to that sushi.
But despite undergoing tests designed to make people sick, no participants have ever actually done the technicolor yawn in the lab.
"We're interested in how [motion sickness] begins, not how it ends," Stoffregen says. "No on has ever thrown up in my lab. And that's a record I'm proud to keep."

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