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     Remeron
     

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Drug Uses

Remeron Tablets are indicated for the treatment of major depressive disorder. Remeron is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide.

How Taken

Remeron is available in a regular tablet formulation (Remeron) that should be swallowed with water. The recommended starting dose for Remeron Tablets is 15 mg/day, administered in a single dose, preferably in the evening prior to sleep.

Warnings/Precautions

Do not take Remeron if you are currently taking, or have taken within the last 14 days, a monoamine oxidase inhibitor. Before taking Remeron, tell your doctor if you have liver disease; have kidney disease; have a manic-depressive disorder; have blood problems; have high or low blood pressure or heart disease; have had a heart attack in the last 6 weeks; or have epilepsy or seizures. You may not be able to take Remeron, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Remeron is in the FDA pregnancy category C. This means that it is not known whether Remeron will harm an unborn baby. Do not take Remeron without first talking to your doctor if you are pregnant. It is not known whether Remeron passes into breast milk. Do not take Remeron without first talking to your doctor if you are breast-feeding a baby. If you are over 60 years of age, you may be more likely to experience side effects such as drowsiness, dizziness, unsteadiness, feeling uncoordinated and low blood pressure. You may require a lower dose of this medication.

Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

Possible Side Effects

If you experience any of the following serious side effects, stop taking Remeron and call your doctor immediately or seek emergency medical treatment: an allergic reaction (swelling of the lips, face, or tongue; difficulty breathing); seizures; a fast or irregular heartbeat; or fever, chills, a sore throat, flu-like symptoms, or sores in your mouth or nose. Other, less serious side effects may be more likely to occur. Continue to take Remeron If you experience any of the following serious side effects, stop taking Remeron and call your doctor immediately or seek emergency medical treatment: drowsiness; nausea; increase in weight or appetite; dizziness; dry mouth; constipation; or mild tremor. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Store at controlled room temperature 20°- 25° C(68°- 77° F). Dispense in a tight, light resistant container.

Overdose

Signs and symptoms reported in association with overdose included disorientation, drowsiness, impaired memory, and tachycardia. There were no reports of ECG abnormalities, coma or convulsions following overdose with Remeron alone. Seek emergency medical attention.

More Information

Use caution when driving, operating machinery, or performing other hazardous activities. Remeron may cause drowsiness and dizziness. If you experience drowsiness or dizziness, avoid these activities. Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. Avoid the use of alcohol while taking Remeron. Alcohol may increase drowsiness and dizziness.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.




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It is our goal to provide a wide range of information and products for health, including the full continuum of health care options and philosophies.

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The reports in the New England Journal of Medicine found a higher risk of developmental problems affecting the intestines, brain and skull. Although life-threatening, all of the defects are rare and normally occur in no more than one in 2,500 births. "The take-home message is that we are talking about very small risks," said UC San Diego epidemiologist Christina Chambers, who has studied the effects of antidepressants but wasn't involved in the new research. The studies are the latest to raise concerns about the effects of antidepressants on fetuses. Babies born to women on antidepressants have been shown to experience signs of withdrawal, including tremors and sleep disturbances, during the first days of life. Others studies have linked a mother's antidepressant use later in pregnancy to an increased risk of lung problems in newborns. Two reports have tied the drug Paxil, in particular, to a higher rate of congenital heart malformation. The drug carries a warning about heart defects. The latest studies were the largest yet to analyze the association between antidepressants and birth defects. The findings could complicate decisions by pregnant women about whether to use or continue taking antidepressants, because untreated depression also carries risks and can lead to smoking, drinking and other harmful behaviors. An estimated 10% of pregnant women have depression, according to previous research. Women should not discontinue antidepressants without first talking with their doctors, the researchers said. The studies focused on antidepressants known as selective serotonin reuptake inhibitors, a class that includes Paxil, Prozac, Zoloft and Celexa. The medications work by enhancing the activity of the brain chemical serotonin. They have become the standard treatment for depression since their introduction in the 1980s. In addition to acting on the brain to improve mood, serotonin constricts blood vessels and performs other functions. The full impact of manipulating serotonin levels within the body isn't completely understood, although animal studies have detected a role for serotonin in prenatal development of the heart and head.

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