Drug Uses
Remeron Tablets are indicated for the treatment of major depressive disorder. Remeron is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide.
How Taken
Remeron is available in a regular tablet formulation (Remeron) that should be swallowed with water.
The recommended starting dose for Remeron Tablets is 15 mg/day, administered in a single dose, preferably in the evening prior to sleep.
Warnings/Precautions
Do not take Remeron if you are currently taking, or have taken within the last 14 days, a monoamine oxidase inhibitor.
Before taking Remeron, tell your doctor if you have liver disease; have kidney disease; have a manic-depressive disorder; have blood problems; have high or low blood pressure or heart disease; have had a heart attack in the last 6 weeks; or have epilepsy or seizures.
You may not be able to take Remeron, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Remeron is in the FDA pregnancy category C. This means that it is not known whether Remeron will harm an unborn baby. Do not take Remeron without first talking to your doctor if you are pregnant.
It is not known whether Remeron passes into breast milk. Do not take Remeron without first talking to your doctor if you are breast-feeding a baby.
If you are over 60 years of age, you may be more likely to experience side effects such as drowsiness, dizziness, unsteadiness, feeling uncoordinated and low blood pressure. You may require a lower dose of this medication.
Missed Dose
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.
Possible Side Effects
If you experience any of the following serious side effects, stop taking Remeron and call your doctor immediately or seek emergency medical treatment: an allergic reaction (swelling of the lips, face, or tongue; difficulty breathing); seizures; a fast or irregular heartbeat; or fever, chills, a sore throat, flu-like symptoms, or sores in your mouth or nose.
Other, less serious side effects may be more likely to occur. Continue to take Remeron If you experience any of the following serious side effects, stop taking Remeron and call your doctor immediately or seek emergency medical treatment: drowsiness; nausea; increase in weight or appetite; dizziness; dry mouth; constipation; or mild tremor.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Storage
Store at controlled room temperature 20°- 25° C(68°- 77° F). Dispense in a tight, light resistant container.
Overdose
Signs and symptoms reported in association with overdose included disorientation, drowsiness, impaired memory, and tachycardia. There were no reports of ECG abnormalities, coma or convulsions following overdose with Remeron alone. Seek emergency medical attention.
More Information
Use caution when driving, operating machinery, or performing other hazardous activities. Remeron may cause drowsiness and dizziness. If you experience drowsiness or dizziness, avoid these activities.
Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
Avoid the use of alcohol while taking Remeron. Alcohol may increase drowsiness and dizziness.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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An antidepressant, in the most common usage, is a medication taken to alleviate clinical depression or dysthymia ('milder' depression). Several groups of drugs are particularly associated with the term, notably MAOIs and tricyclics (whose serendipitous discovery and psychiatric use dates from the 1950s) as well as SSRIs and more recent variations developed by pharmaceutical companies. These medications are now amongst the most commonly prescribed by psychiatrists and general practitioners, and their effectiveness and adverse effects are the subject of many studies and competing claims. A number of other antidepressant drugs, notably St John's Wort, are also widely studied and used.
Antidepressants are generally, if not in pharmacology, considered separately from stimulants. They are usually taken as a course over several weeks, months or years, and have a delayed onset of therapeutic action. Drugs used for an immediate euphoric effect only are not generally considered antidepressants. Despite the name, antidepressants are often used in the treatment of other conditions, including anxiety disorders, bipolar disorder, eating disorders and chronic pain. Some have also become known as lifestyle drugs, sometimes referred to as "mood brighteners". Conversely other medications not known as antidepressants, including antipsychotics in low doses and benzodiazepines are also widely used to manage depression. In fact the antidepressant term is sometimes applied to any therapy (e.g. psychotherapy, electro-convulsive therapy, acupuncture) or process (e.g. sleep disruption, increased light levels, regular exercise) found to improve clinically depressed mood. It is also the case that placebos tend to have a significant antidepressant effect, so that establishing something as an antidepressant in a clinical trial involves demonstrating a significant additional effect.
The most commonly prescribed antidepressants in the US in 2005 were:
* Sertraline - of the SSRI class (e.g. Zoloft, Lustral, Apo-Sertral, Asentra, Gladem, Serlift, Stimuloton)
* Escitalopram - of the SSRI class (e.g. Lexapro, Cipralex)
* Fluoxetine - of the SSRI class (e.g. Prozac, Sarafem, Fluctin, Fontex, Prodep, Fludep, Lovan)
* Venlafaxine - of the SNRI class (e.g. Effexor XR, Efexor)
* Citalopram - of the SSRI class (e.g. Celexa, Cipramil, Talohexane)
* Paroxetine - of the SSRI class (e.g. Paxil, Seroxat, Aropax)
* Trazodone - of the Tetracyclic class (e.g. Desyrel, Trazolan)
* Amitriptyline - of the TCA class (e.g. Elavil)
* Bupropion - of the DRI and NRI classes (e.g. Wellbutrin, Zyban)
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